The phrase "strike home" has numerous synonyms, and it refers to a statement or act that has a profound impact on someone. Some common synonyms for "strike home" are "hit the nail on the head," "resonate," "strike a chord," "hit home," "cut to the heart," and "hit the mark." Using these synonyms can help convey the same emotions and messages as "strike home" while avoiding repetition in your writing. For example, you could say, "Her words hit me like a ton of bricks and really struck a chord with me," instead of saying "Her words really struck home with me".