Scuzzball is a derogatory slang term used to describe someone who is dirty, sleazy, low-class, or generally unpleasant. It can be difficult to find synonyms for this word that are both equally derogatory and appropriate for different contexts. Some synonyms that might be used for scuzzball include slimeball, creep, dirtbag, lowlife, sleazebag, jerk, and loser. These words are all derogatory and negative, implying a lack of moral character or decency. While scuzzball may be a popular insult in some settings, it's important to remember to use language that is respectful and appropriate for the situation at hand.