The words "most unstressed" contain a superlative modifier denoting extreme degree of lack of stress. The antonyms or opposites of the word "most unstressed" refer to varying degrees of being stressed. The words "high-strung," "overworked," or "tense" express the opposite of being relaxed or calm. Alternatively, using the word "stressed" in a less extreme form, we can have synonyms such as "anxious," "concerned," or "worried." While the word "most unstressed" conveys a positive connotation, its antonyms convey the negative feeling of pressure or tension in a person's life, whether it be from work, family, or other sources.